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Jennifer Jason Leigh stars as Sarah Andrews in the classic '80s sitcom "Sister, Sister." The show follows the comedic adventures of two sets of twins who were separated at birth and later reunited. As one half of the adopted Wentworth siblings, Sarah is a smart, sassy, and resourceful teenager navigating life with her quirky twin brother Toby. Leigh's portrayal of Sarah showcases her incredible range as an actress, balancing humor and heart in every scene. Her chemistry with co-star Marquise McCoo, who plays Toby, is undeniable, making their sibling dynamic both endearing and entertaining to watch. In "Sister, Sister," Jennifer Jason Leigh proves herself a master of comedy, delivering laughs while also touching on deeper themes like family, identity, and the importance of love and connection in our lives.